characterization of carbapenemases in extensively drug resistance acinetobacter baumannii in a burn care center in iran

نویسندگان

leila azimi antimicrobial resistance research center, iran university of medical sciences, tehran, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (iran university of medical sciences)

malihe talebi department of microbiology, iran university of medical sciences, tehran, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (iran university of medical sciences)

mohammad-reza pourshafie department of bacteriology, pasteur institute of iran, tehran, iran.سازمان اصلی تایید شده: انستیتو پاستور ایران (pasteur institute of iran)

parviz owlia molecular microbiology research center, shahed university, tehran, iran.سازمان اصلی تایید شده: دانشگاه شاهد (shahed university)

چکیده

the emergence of multidrug resistance (mdr) and extensively drug resistance (xdr) in acinetobacter baumannii has made an important challenge in the treatment of infections caused by this organism. the ability of carbapenemase production is one of the main mechanisms for the emergence of mdr and/or xdr in a. baumannii. the aim of this study was to detect carbapenemase producer a. baumannii. in this study, 65 imipenem resistant a. baumannii were collected from burned patients. biochemical identification, antibiotic susceptibility test and multiplex polymerase chain reactions for the detection of carbapenemases genes were performed. the results showed that all strains carried blaoxa-51. 83%, 12.5% and 9.23% strains harbored blaoxa-23, blavim and blakpc genes, respectively. none of the isolates carried blaimp, blaoxa-48, blandm-1 and blaspm-1 genes. the results of this study indicate the emergence of klebsiella pneumoniae carbapenemase (kpc) in a. baumannii causing nosocomial infections in burned patients which can be important for hospital infection prevention systems in iran.

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Characterization of Carbapenemases in Extensively Drug Resistance Acinetobacter baumannii in a Burn Care Center in Iran

The emergence of multidrug resistance (MDR) and extensively drug resistance (XDR) in Acinetobacter baumannii has made an important challenge in the treatment of infections caused by this organism. The ability of carbapenemase production is one of the main mechanisms for the emergence of MDR and/or XDR in A. baumannii. The aim of this study was to detect carbapenemase producer A. baumannii. In t...

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Characterization of Carbapenemases in Extensively Drug Resistance Acinetobacter baumannii in a Burn Care Center in Iran

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عنوان ژورنال:
international journal of molecular and cellular medicine

جلد ۴، شماره ۱، صفحات ۴۶-۵۳

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